A high hepatitis B viral load in a pregnant woman does not affect the growth and development of the fetus, but increases the likelihood of intrauterine infection, which means that the baby’s chances of developing hepatitis B after birth increase. For this situation, pregnant women need to take oral tenofovir during pregnancy for mother-to-child interruption: if the hepatitis B virus quantification of pregnant women is eight to nine times, which is a very high value, pregnant women should start taking oral tenofovir at 20 weeks of pregnancy; if the hepatitis B virus quantification of pregnant women is six times or seven times, you can start taking oral tenofovir at 24 weeks; if the hepatitis B virus quantification of pregnant women is five times, you can start taking oral tenofovir at 24 weeks of pregnancy; if the hepatitis B virus quantification of pregnant women is five times, you can start taking oral tenofovir at 24 weeks of pregnancy. If a pregnant woman’s hepatitis B viral load is five times higher, she can start taking oral tenofovir at the 28th week of pregnancy. Pregnant women who take oral tenofovir still need to inject hepatitis B vaccine and hepatitis B immunoglobulin after the birth of their fetus.