Discomfort in the throat requires the selection of appropriate examination methods according to the individual condition and the medical conditions available in the selected medical institution; there is no most comprehensive examination, only a more comprehensive one. Throat discomfort can be related to inflammation, tumor, foreign body, congenital developmental abnormality and systemic diseases, etc., and the corresponding symptoms include: foreign body sensation in the throat, coughing, coughing up sputum, blood in sputum, hoarseness, dyspnea, dysphagia, and swallowing obstruction. Clinically, we can use electronic fiberoptic laryngoscopy, laryngeal CT, magnetic resonance, color ultrasound, pharyngeal esophageal Ph 24-hour monitoring, esophageal manometry, PET-CT and other examinations to comprehensively determine the status of the disease in terms of the structure and function of the pharynx. If you have any throat discomfort, you need to consult the doctor in time, and make targeted treatment after the doctor’s examination.