There are chances of success in artificial insemination, and failing once does not suggest giving up easily, but it needs to be analyzed on a case-by-case basis. The success rate of artificial insemination is 10-20%. One unsuccessful is not recommended to be frustrated, under normal circumstances, after more than 3-4 times of artificial insemination, if unsuccessful pregnancy is recommended to fully communicate with the doctor to further search for factors leading to infertility, whether to take other ways of assisted conception. If the woman’s pelvic environment is poor, suffering from chronic pelvic inflammatory disease or endometriosis, the tubal imaging test suggests that the passage is not smooth, at the same time, the male partner’s semen condition is poor, you can consider further options for in vitro fertilization. Artificial insemination is possible to continue to adhere to if it fails once, but it also needs to be analyzed according to the specific situation.