Mild pyriform muscle syndrome oral medication conservative treatment is possible to cure, for the pyriform muscle edema is heavier, may only be able to alleviate the symptoms. Piriformis syndrome is caused by the proliferation and hypertrophy of the piriformis muscle, which compresses the sciatic nerve located under the piriformis muscle and causes pain and numbness in the area of sciatic nerve innervation and limited movement. The compression of the sciatic nerve can produce localized edema, sterile inflammation and poor local blood circulation. Oral medication, such as non-steroidal anti-inflammatory drugs and proprietary Chinese medicines that activate blood circulation and improve local circulation, can alleviate the patient’s symptoms and may cure mild cases, but in severe cases of edema, it can only relieve the symptoms of compression. The treatment of pyriformis syndrome is a comprehensive treatment, conservative treatment is ineffective need for surgical treatment, in the operation to loosen the hypertrophy of the pyriform muscle, a complete cure for pyriformis syndrome.