When a patient is vaccinated with Neocrown vaccine in the case of high pressure of 160 mmHg, no special intervention is needed if there are no special symptoms, and if any adverse reaction occurs, the health care provider should be informed promptly to make appropriate treatment measures. Patients with hypertension can only be vaccinated if their blood pressure is below 160/100mmHg and they are in the chronic phase of the disease that can be controlled by antihypertensive drugs. When the blood pressure reaches 160 mmHg and the vaccine is administered, there is no need to be nervous if there are no symptoms, so take some antihypertensive drugs and observe the rise and fall of the blood pressure after informing the medical staff and the vaccinators. If the blood pressure continues to rise after vaccination, and symptoms such as chest tightness, shortness of breath, and cyanosis appear, it is necessary to seek medical attention promptly to see if there is an adverse reaction to the drug and to treat accordingly under the guidance of a clinician. After the injection of New Crown vaccine, patients with hypertension need to take antihypertensive drugs regularly and actively control their blood pressure. Contraindications to New Crown vaccination include allergy to vaccine components, pregnant women during pregnancy, those with psychiatric disorders, and fever of any cause, patients with acute heart disease, gout, etc.