Liver cancer is usually considered as an incurable malignant tumor, and the global incidence of primary liver cancer (Hepatocellualr carcinoma, HCC) ranks fifth in malignant tumors and second in mortality rate, with nearly 400,000 new cases of liver cancer in China every year and mortality rate close to 90%. Because most people do not know the causes of liver cancer, many chronic liver diseases including viral hepatitis, fatty liver, alcoholic liver disease and liver cirrhosis may develop into liver cancer, and there are usually no special symptoms in the early stage of liver cancer, which makes liver cancer patients who could be detected in time miss the best treatment time. As a matter of fact, with the advancement of modern medical diagnosis and treatment technology, if liver cancer can be detected early and treated reasonably, it is not an empty phrase to cure liver cancer completely. Which special groups are prone to get liver cancer? Mainly, they include chronic hepatitis B (HBV)/hepatitis C (HCV) virus infection, long-term heavy drinking (especially alcoholic cirrhosis), smoking, heavy fatty liver, family history of liver cancer, long-term consumption of moldy or spoiled food or drinking contaminated water, etc. For such high-risk groups, I again strongly recommend that they should have a comprehensive medical checkup at least once every 3 months to 6 months, and the examination items include: tumor markers (AFP, CA19-9, CEA), abdominal ultrasound, liver function, virological indexes (Hepatitis B 5, Hepatitis B DNA quantification), and if liver occupancy is suspected, further enhanced CT or MRI examination is needed, and tissue puncture biopsy can be chosen if necessary. It is best to bring family members along for medical examination, especially the spouse and children of viral hepatitis infected patients (HBV/HCV). Surgery is the preferred treatment for liver cancer If the patient is in good health when diagnosed with liver cancer, the cirrhosis is not serious, the liver function is basically normal and the tumor has the conditions for surgical resection, the comprehensive treatment based on liver resection surgery should be preferred; in addition, for some patients with liver cancer with smaller diameter and deeper location, ablation therapy can also be chosen; while for those patients with very serious cirrhosis, poor liver function and not very large tumor However, for those liver cancer patients who can neither be surgically removed nor receive liver transplantation, they need to choose interventional, drug or TCM treatment according to their specific conditions. Since the condition of each liver cancer patient at the time of tumor discovery is not exactly the same, individualized treatment should be adopted according to each person’s condition. Therefore, it is wise to go to a comprehensive regular hospital with all kinds of treatment methods for liver cancer treatment. After surgical removal of lesions, some liver cancer patients may experience tumor recurrence or metastasis within a period of time, which is one of the important reasons why liver cancer is difficult to be cured. In order to improve the treatment effect of liver cancer, I suggest that liver cancer patients must take the initiative to have regular checkups and follow-up adjuvant treatment after surgery, and we still have methods to treat liver cancer even if it recurs. Regular check-up plan and early post-operative issues I suggest that patients with liver cancer should be re-examined every 1-2 months in the 1st-2nd years after receiving surgery, and the examination items include tumor markers (AFP, CA19-9, CEA), abdominal ultrasound, liver function, etc. If there is hepatitis virus infection, the viral infection status should also be checked, and enhanced CT or MRI examination should be done every six months. After the 3rd year after surgery, the examination should be repeated every 2-3 months, and the examination items should be the same as before. In addition, it is necessary to be alert to the possibility of extrahepatic metastasis of tumor, and chest X-ray should be done once every six months, and isotope bone scan should be done if bone metastasis is suspected. In the early stage after liver cancer surgery, it is easy to have loss of appetite, abdominal distension and easy satiety, which usually will gradually improve with time. The amount of fat intake should be limited, especially not to eat too much animal fat at one time, avoid too much cold food, and not to exercise too much after meals. In addition, the symptoms of discomfort after surgery are easy fatigue and wound pain, you can take appropriate pain medication, do not worry too much about drug addiction. For the first 6 weeks after surgery, it is not suitable to move heavy objects over 5 kg with one hand or both hands. Nutritional issues of liver cancer patients after surgery can be referred to my previous article “Post-surgical diet considerations for liver cancer – what can be eaten? What are not recommended to eat? In principle, both normal people and liver cancer patients emphasize the reasonable combination of diet structure and nutritional balance. Avoid eating processed (smoked, pickled, sauced, baked, fried) and stimulating (spicy, acid, too salty, too hot, too much gas) foods. What interventional treatment should be done after hepatocellular carcinoma resection surgery? Transhepatic artery cannulation chemoembolization (TACE) can play two roles: on the one hand, it can detect small metastatic lesions in the liver at an early stage and cut off the blood supply to the tumor through embolization to help the subsequent treatment; on the other hand, it can infuse chemotherapy drugs locally in the liver to improve the effectiveness of anti-tumor drugs and reduce drug side effects. I usually recommend to do the 1st intervention in the 1st month of follow-up after liver cancer surgery, and if there is no recurrence during the follow-up period, TACE can be done every 3-4 months, and 3-4 interventions in the 1st year after surgery, and then decide whether TACE is needed again according to the situation, in addition, the number of TACE needs to be decided according to the patient’s response and tolerance during the treatment period, and I oppose to disregard I am against blind chemotherapy without regard to the patient’s nutritional status, physical strength and side effects, which will do more harm than good to the treatment of tumor and even cause serious damage to liver function. Anti-viral therapy for postoperative hepatocellular carcinoma related to viral infection is essential. Active antiviral therapy can reduce the recurrence rate of hepatocellular carcinoma after surgery while slowing down the development of liver fibrosis and protecting liver function. What if the tumor recurs after surgery? If patients can be operated, they can be operated again or undergo remedial liver transplantation; for those who cannot be operated temporarily, they can also take liver artery embolization, ablation, targeted drugs and other treatments while liver preservation treatment, and if the tumor shrinks, it can be removed in the second stage. Even for those patients who cannot be surgically removed, palliative means can be used to continue the flame of life as much as possible.