Hepatic artery chemoembolization combined with radiofrequency ablation is the treatment of choice for large hepatocellular carcinoma that cannot be surgically resected. Both hepatic artery chemoembolization and radiofrequency ablation are highly precise treatments with complementary efficacy, which significantly increase the success rate of treatment, reduce the recurrence and metastasis of tumor, reduce the number of treatments, and achieve the effect close to that of surgical operation. ”Hepatic artery interventional embolization chemotherapy” is one of the most commonly used effective treatments for liver cancer, which requires multiple treatments to achieve good results. The combination of “arterial embolization chemotherapy” and “radiofrequency ablation” treatment is to give radiofrequency ablation treatment after “arterial embolization chemotherapy”. Radiofrequency ablation treatment is to puncture the cold-polar radiofrequency needle or multi-polar radiofrequency ablation needle to the tumor treatment site under the guidance of B-ultrasound or CT, and to produce high temperature to the tumor cells through radiofrequency energy to achieve coagulative necrosis. The use of this combined treatment technique requires qualified hepatic oncologists to select cases with good coagulation function, no large amount of ascites, etc. The site of the tumor in the liver also needs to be screened, which is suitable for patients with primary treatment or recurrence, and still effective for patients with poor efficacy of interventional embolization. This treatment has been widely used and has a curative effect not only on hepatocellular carcinoma less than 4 cm, but also on large hepatocellular carcinoma.