Pimples are usually referred to as acne. Redness and swelling after squeezing acne may be due to bacterial or other infections, which can be treated with topical or systemic medication. Acne is most common in teenagers. If unhygienic utensils or bare hands are used to squeeze acne, bacterial infections may occur, resulting in redness and swelling, which can be treated with topical fusidic acid cream, oral minocycline and other medications for anti-infective treatments, and oral vasic acid drugs under the guidance of a doctor for severe symptoms. In addition, patients should wash their skin with water or choose appropriate cleansing products, pay attention to sun protection, and avoid squeezing acne with hands or unhygienic utensils, which may aggravate the local infection. It is not recommended that patients with acne squeeze the affected area by themselves. If redness or swelling occurs after squeezing, it is recommended to go to a regular hospital in time and receive standardized treatment under the guidance of a doctor.