Taking cefradine for periodontitis is of limited use. Periodontitis is indeed an inflammation of periodontal tissues, and it is the primary risk factor leading to total tooth loss in middle-aged and elderly people, and the main cause of it is poor periodontal hygiene, retaining a large amount of plaque and calculus, the proliferation of plaque and calculus, the formation of gum inflammation, gingivitis long-term without intervention, the gradual formation of gum recession and alveolar bone resorption, the formation of periodontitis, from this In this regard, the application of broad-spectrum cephalosporin antibiotics has a certain role. In practice, for periodontitis, the primary treatment is to remove the causative factors, that is, the need to remove the periodontal plaque and calculus, the method of removal needs to go to a professional dentistry, the application of supragingival scaling and subgingival scraping, combined with root surface leveling approach, to clean the periodontal plaque and calculus thoroughly, and then consider the application of local drugs, or systemic drugs to control inflammation. In the absence of local control of calculus and plaque, the application of any anti-inflammatory drug for periodontitis is not particularly effective.