The treatment of tuberculosis in the elderly needs to take into account the safe, effective and rational use of medication, and the need to choose the best individual treatment program does not exist in the best treatment. Due to the existence of unique physiological and pathological characteristics of the elderly, in the level of drug safety range, drug effectiveness is subject to certain constraints, can not be generalized to use a fixed uniform treatment model, according to the patient’s specific situation to make specific adjustments in order to choose the best individual treatment plan, so there is no optimal treatment. In addition, due to the existence of certain adverse reactions to anti-tuberculosis drugs, such as certain drugs have a certain degree of hepatotoxicity, nephrotoxicity, etc., the elderly in the process of taking anti-tuberculosis treatment need to be properly adjusted drug program. In the course of treatment, it is also necessary to closely monitor the adverse effects of the drugs and adjust the treatment program in time if necessary. At the same time, due to the poor memory ability of some elderly people, it is also necessary to strengthen supervision during the treatment process to ensure that patients take the medication on time, according to the regularity and dosage, so as to ensure the success of the treatment and prevent the development of drug resistance.