Always stomach pain in the middle of the night mainly consider three causes, as follows: 1, the most common is duodenal ulcer, duodenal ulcer often has night pain, hunger pain and other characteristics, when eating and taking acid suppressants, abdominal pain, acid reflux and other symptoms will gradually ease. 2, gastroesophageal reflux disease, eating too much fatty food at dinner, flat rest may appear after acid reflux, heartburn, pain behind the sternum and other symptoms. 3, some Normal people who have not eaten for a long time at night, vagus nerve excitement, too much stomach acid in the stomach, and no timely food after neutralizing the stomach acid, will also appear acid reflux, heartburn, and even spasmodic pain in the smooth muscle of the stomach, such cases mostly have a history of chronic gastric mucosal damage. Therefore, it is recommended that patients should eat a warm, soft, light and easily digestible diet, avoid spicy and stimulating food intake, avoid overeating, develop good eating and rest habits, avoid staying up late, and exercise appropriately to enhance physical fitness.