Patient Li Mou twenty years ago began to slight hand tremor, Li Mou did not pay attention. Unexpectedly, this hand shaking “small disease”, but is Parkinson’s disease! When she knew the truth, it was too late. The disease has entered the most serious stage, Li Mou has been unable to take care of herself, eating and speaking are difficult. Li went around seeking medical treatment, and finally underwent a successful surgery in our hospital. The following is a simplified case of Li’s, which can be used as a reference for all patients. Name: Li XX Gender: female Age: 63 years old Admitted for “involuntary shaking of hands for 20 years, limb stiffness and tremor for 8 years” Characteristics of the case: 1. Elderly female, chronic course of the disease. 2. 20 years ago, the patient had involuntary slight shaking of the hands without any obvious cause, obvious when holding things, bilateral simultaneous onset of the disease, no limb activity stiffness, walking difficulties, etc., not taken seriously, There was no stiffness in limb movement, difficulty in walking, etc., and no attention was paid to it. In 2006, when he was playing Tai Chi, he felt that his movements were not in place, his limbs were stiff and slow, and his limbs were in static tremor, and he was hospitalized in the Neurology Department of our hospital and diagnosed with Parkinson’s disease, and the specific treatment was not known. In 2007, he had “intermittent claudication” and was hospitalized in a number of hospitals to rule out “vascular disease”. In 2009, she started to take oral medication of Metobar and Antan, but the effect was not obvious. Symptoms gradually aggravated, and now the limbs are stiff, inactivity, self-perception of the right upper limb and double lower limbs heavier, slow movement, double upper limb tremor, slurred speech, choking on drinking water, swallowing is relatively normal, turning over difficult, not drooling, walking posture, gait abnormal, life can not take care of themselves. She took Metobarb and Senflo, which were effective for rigidity and tremor, with an onset of effect in 1 hour, maintained for 1-2 hours, and was able to walk for half an hour after the onset of effect. She came to the outpatient clinic for further diagnosis and treatment, and was admitted to the hospital with “Parkinson’s disease”. Since the onset of Parkinson’s disease, she has been in a bad mood, has poor sleep, eats well, has severe constipation, and urinates normally with the use of Kefir. Preliminary diagnosis: Parkinson’s disease Treatment: After admission, he actively improved the relevant examinations, without obvious contraindications to surgery, and underwent stereotactic bilateral deep brain electrode implantation + thoracic pulse generator implantation under general anesthesia successively. The surgery went smoothly. At the time of discharge: the patient had no special discomfort, and his mental state was good. Vital signs were stable, no fever. Director Wang instructed that the patient had recovered well and could be discharged from the hospital. Parkinson’s disease has an insidious onset, the initial symptoms are not easy to detect, and it is not easy to cause people’s vigilance, which will easily lead to miss the best treatment time, and the treatment effect will be greatly reduced. “Shaking, stiffness and slowness” are common symptoms of Parkinson’s disease, which are motor symptoms. In fact, the earliest symptoms of Parkinson’s disease should be non-motor symptoms, such as depression and anxiety. So how is Parkinson’s disease treated? “Parkinson’s disease is a chronic disease that is controlled by lifelong medication, but the medication will have an expiration date. By the time the disease is at the end of its course, the medications play a very small role, so surgery is added to the treatment. Deep Brain Electrical Stimulation (DBS) is a proven and safe treatment that is very effective in improving Parkinson’s symptoms. However, the exact effectiveness of the surgery varies from person to person and requires a detailed checkup and evaluation at the hospital.”