In severe bacterial infections, the first step is to use powerful antibacterial drugs to control the infection. If you do not know what kind of bacterial infection, before using antibacterial drugs for treatment, take samples from the site of infection, blood, urine, sputum or cerebrospinal fluid, etc., conduct bacterial culture to clarify the type of bacteria, and conduct antibacterial drug sensitivity tests, referred to as drug sensitivity tests; based on the infection, speculate on the bacteria that may cause the infection, and use a combination of antimicrobial drugs with a wide range of antibacterial and strong antibacterial ability to control the infection, and the selected The selected antimicrobial drugs must ensure that they can work at the site of infection. When the bacterial culture and drug sensitivity results are available, the antibacterial drugs will be adjusted according to the situation. If the infected area has been septic or must be surgically resolved, it should also be promptly treated by incision and drainage or surgery. The patient’s accompanying high fever, shock, acid-base imbalance, electrolyte disturbance, and complications of the heart, lungs, kidneys, brain, and other organs should also be actively managed.