Clinically, through sexual transmission, pregnant women can be infected with mycoplasma vaginitis. Pregnant women who have increased vaginal discharge, yellow color, vulvar itching, discharge odor, or at the same time accompanied by frequent urination, urinary urgency, urinary prick itching and pain, vaginal discharge, urine mycoplasma culture, nucleic acid test positive, indicating that pregnant women suffer from vaginal or (and) urethral mycoplasma infection. Mycoplasma infection in early pregnancy can cause miscarriage, and mycoplasma infection in late pregnancy can cause preterm labor and postpartum neonatal infection. Mycoplasma infections in pregnant women need to be treated aggressively, choosing medications that do not have a significant effect on the fetus and minimizing the side effects of the medications. Generally use azithromycin, erythromycin, sufficient amount, sufficient course of treatment to cure mycoplasma infection, sexual partners check positive also need to be actively treated. Pregnant women usually drink more water as appropriate, keep the vulva clean, change and wash underwear diligently.