After a perforated appendix, the pain may be relieved for a short period of time, but if left untreated, the pain may continue to worsen. Appendicitis is an acute abdominal condition whose first symptom is abdominal pain, typically “metastatic right lower abdominal pain”. Before perforation of the appendicitis, the pressure in the lumen is very high, and the nerve is stimulated, so the pain is obvious. Once the pressure in the appendiceal cavity suddenly decreases after perforation, the abdominal pain can be temporarily reduced or even disappear. At this point, the infection has spread to the peritoneal cavity, and the abdominal pain will continue and intensify after peritonitis develops. Therefore, it is very urgent to consult a doctor immediately to find out the cause of this condition. If the diagnosis is perforated appendicitis, immediate surgical treatment is needed, such as laparoscopic appendectomy, with bed rest, and postoperative treatment with anti-infective drugs as prescribed by the doctor, such as ceftriaxone sodium, levofloxacin and so on.