Positive HPV type 45 means that the body is infected with human papillomavirus type 45. If the patient’s liquid-based thin layer cell test does not reveal cervical cancer, it is usually not serious. If cervical lesions are found after the liquid-based thin layer cell test, it is more serious. Positive HPV type 45 indicates infection with human papillomavirus type 45, which is a high-risk type of human papillomavirus. If there is only a simple HPV 45 positivity and no abnormality on liquid-based thin layer cell test, it is usually not serious and the patient can be observed first and reviewed regularly. If HPV type 45 infection persists and cervical lesions are detected by the liquid-based thin layer cell test, it may cause cervical lesions and cervical cancer, which are more serious. Whether the infection of HPV type 45 is serious or not requires timely medical treatment, and the doctor will judge whether the condition is serious or not based on whether cancerous lesions appear in the cervical area. It is recommended that patients ensure enough rest, appropriate physical exercise to improve the body’s immunity.