Patients with acute tonsillitis do not necessarily need to be treated with infusion, they can choose oral or infusion treatment according to the severity of the condition, they can first use penicillin antibiotics for oral treatment, such as amoxicillin capsules for oral treatment, if the effect is not good, they can switch to cephalosporins for oral or infusion treatment. If the patient’s symptoms are serious and the fever persists for a few days, consider whether there is a combination of anaerobic bacterial infection, which may require simultaneous treatment with cephalosporins and anti-anaerobic drugs such as metronidazole and tinidazole, or switch to quinolone antibiotics for treatment, which can be considered intravenous infusion therapy at this time. So acute tonsillitis can be treated either orally or by infusion, depending on the severity of the patient’s condition and the type of infection.