Creatinine is a metabolic waste of the human body, which is mainly metabolized and discharged through the kidneys, so the creatinine level can reflect the good or bad kidney function. Creatinine will rise only when kidney function is impaired by more than half, and when creatinine reaches more than 300, it has often entered the fourth stage of chronic kidney disease, and further development is uremia. For its treatment, first of all, the cause must be clear, more common is caused by chronic nephritis, you can take oral Bailing capsule to protect the kidneys and urinary toxicity particles to reduce creatinine, while oral medication to control blood sugar, blood pressure, blood lipids, the integration of these chronic kidney disease treatment can slow down the speed of creatinine increase. If there is a sharp increase in creatinine, you need to find the cause of the rapid progression of kidney function, targeted treatment for the cause, to prevent the emergence of uremia.