Creatinine 300umol/L is not considered normal and is already relatively high. Creatinine is a metabolic waste of the human body, mainly produced by muscle tissue metabolism, of which 99% of creatinine is excreted through the kidneys. Therefore, after the creatinine is elevated, it often represents a decline in kidney function and renal insufficiency, caused by more common causes such as glomerulonephritis, IgA nephropathy, diabetic nephropathy and hypertensive kidney damage. For this situation, you need to go to the nephrology department of the hospital for further examination of the causes of creatinine elevation, as well as the application of Bailing Capsules to protect the kidneys, and Urotoxic Cleansing Granules to reduce creatinine symptomatic treatment. If it is some acute kidney injury, such as acute interstitial nephritis, acute tubular necrosis and other factors that lead to elevated creatinine, it is possible to return to normal after active drug treatment. If the creatinine is elevated due to some chronic diseases, it needs long-term regular medication to prevent further impairment of kidney function. When creatinine exceeds 700umol/L, it is uremia and needs dialysis treatment.