Scabies is a chronic infectious skin disease caused by the scabies mite parasitizing the human epidermis. It is highly contagious and spreads easily in families and groups. Children are easily misdiagnosed because of the thin and tender skin and the atypical manifestation of symptoms. The rash in children appears as a scattered distribution of papules and papules ranging from pinpoint to corn-like in size. There may be small blisters, tunnels, eczema-like lesions, nodules, and even purulent infections. Rub 5% sulfur cream all over the child’s body after bathing, 1-2 times a day for 3 days, and then bathe and change clothes after the 4th day. Boil all the changed clothes, sheets and toys to eliminate insects. Wash the items that cannot be boiled for 1 week after sealing or expose them to the sun for 1 day. Treat with antibacterial medication at the same time if septic infection occurs. Add antihistamines if eczema-like changes or nodules are more frequent. If not cured, continue treatment for 1-3 courses (rubbing only on the lesions). Patients in the family or those in close contact with the child should be treated together. Adult patients should be treated with 10% sulfur cream for 1 to 2 weeks.