Scabies has developed in all countries of the world, and scabies was recorded in China as early as the 14th century B.C. Before the founding of the People’s Republic of China, scabies was prevalent in a large number of rural towns in China and was eradicated for a time after the founding of the People’s Republic of China, but since the 1970s there have been reports of localized epidemics. Scabies is a contact infectious skin disease caused by scabies parasites in the epidermis of human skin. The scabies mite belongs to the class of mites, so it is also called the scabies mite and is parasitic in the skin of humans and mammals, and the life span of the scabies mite is 5 to 6 weeks, and it can only survive for about 72 hours after leaving the skin. The infection of scabies is transmitted through direct contact (including sexual contact) or indirect contact between people, such as living in a bed, shaking hands and other contact methods, or indirect infection through contact with the clothes, bedding, sheets, pillowcases, towels, etc. used by patients. Therefore, the disease occurs mostly in people with poor sanitary conditions and close living contact, especially in people who live in groups, such as boarding students and migrant workers, and often in a family with multiple members. After the scabies mite invades human skin, in addition to mechanical stimulation of the skin, the toxin secreted by the scabies mite can also cause skin metaplasia, causing papules, blisters or pustules on the skin, while causing strange itching. The scabies mite usually likes to invade delicate parts of the skin, such as finger crevices, wrists, elbow sockets, armpits, under the nipples, vulva, groin, etc. The damage to the skin by the scabies mite is not only manifested as tunnels (where the scabies mite burrows through, in the form of a thin grayish or black line), papules, blisters, and pustules, but also nodules the size of green beans to soybeans can appear after infection in the penis, scrotum, labia, and perianal area. The proverb says: “scabies is a dragon, first from the hand slit line, around the waist turn three circles, the pubic part of the big camp”. This very graphically describes the general characteristics of scabies. “Scabies is a dragon”: it means that the symptoms of scabies are generalized, not concentrated in a certain place, and it also means that scabies has a developmental nature, often itchy and indefinite, like a dragon going through; “first from the hand seam line”: the hand seam is the first part to be affected; “three circles around the waist”: the waist is often the main site of onset; “the pubic area is camped out”: scabies often ends up with scabies nodules in the pubic area. The itching symptoms of scabies patients often intensify at night, which is due to the mechanical irritation caused by the female worms starting to dig tunnels at night. In some patients, stimulation such as scratching and water scalding due to itching can cause epidermal exfoliation, blood crusting or secondary infection, resulting in folliculitis and boils. A small number of patients can also be complicated by nephritis. Scabies should be treated immediately in isolation in order to completely eliminate the source of infection. The clothes worn by the patient, used bedding and other items must be disinfected by boiling, or exposed to the sun to kill the scabies mite. The treatment of scabies is mainly based on external medicine, and generally does not require systemic medicine. If the combined infection or eczema, etc. can also be treated with internal medication. Topical medication commonly used sulfur ointment, such as adults with 10% sulfur ointment, children with 5% sulfur ointment, morning and evening applied once. Special attention should be paid to the fact that the ointment should be applied all over the skin of the body except the scalp and the face, and carefully applied at the papules and blisters. Do not bathe or change your clothes during the rubbing period, and use the medicine for 3 to 4 days continuously. In order to keep the drug at a certain concentration, take a thorough bath after 4 days. Change of clothes, bedding, etc. should be disinfected. Generally, it can be cured after 1 to 2 courses of treatment, and the treatment time for scabies in children should be extended appropriately because the concentration of the selected drug is lower in children and the allergic lesions due to hypersensitivity reactions in children will last longer. Observe the treatment for 2 weeks after the end of treatment to determine the efficacy. If there is a recurrence, it should be treated promptly. Prevention of scabies, first of all, we should pay attention to personal hygiene, bathe, change clothes and bedding regularly, do not live with patients, shake hands, and do not use patients’ clothes and bedding, etc. Patients found should be treated in a timely manner, and clothes changed should be boiled to exterminate insects, and things that cannot be boiled and scalded should be wrapped in plastic for a week and then washed after the scabies mites are starved.