According to the patient’s disease type, condition and other differences, cyclosporine need to take the length of time there are also different, can not directly determine how long to take cyclosporine can reduce the dosage. Cyclosporine is a kind of immunosuppressive drug through the specific inhibition of auxiliary T lymphocyte activity, is mainly used in the treatment of myelosuppression, organ transplantation and psoriasis, atopic dermatitis, rheumatoid arthritis and other non-transplantation diseases, the drug is used for the treatment of different diseases, the specific use of the dosage of a greater difference. For example, when cyclosporine is used for the prevention of allograft rejection in organ transplantation, it should be administered in two doses of 15mg/kg/d 12 hours before the transplantation surgery, and the dose should be maintained until 1~2 weeks after the surgery, and then gradually reduced; when used in psoriasis, it is recommended that the starting dose should be 2.5~5.0mg/kg/d orally in two doses, and then the dose should be reduced after the symptoms have improved. Adverse effects of cyclosporine are usually dose-related and can be mitigated by lowering the dose. Increases in plasma creatinine and urea nitrogen levels can occur during the first few weeks of treatment, as well as arterial hypertension, tremor, weakness, headache, infections, and malignant tumors. It is contraindicated in patients with hypersensitivity to cyclosporine and any of its excipients, renal insufficiency, patients with uncontrolled hypertension, patients with uncontrolled infections, and patients with known and confirmed history of malignancy of any type. Take care to monitor hepatic and renal function and blood pressure during administration. Cyclosporine should be used under the guidance of a physician, it is recommended that patients treated with cyclosporine go to the relevant departments of regular hospitals for detailed consultation, do not stop or reduce the drug without authorization.