In general, for the peeling of the foreskin after the application of iodophor, it may be caused by the irritation of iodophor. The foreskin is a double-layered free circular fold formed by the skin in front of the neck of the male penis, which is relatively sensitive and fragile. Povidone-iodine is a strong oxidizing disinfectant commonly used in the clinic. When povidone-iodine is applied to the foreskin, it can be irritating to the foreskin, causing peeling of the foreskin, and even inflammatory reactions as well as allergic phenomena. When povidone-iodine is applied to the foreskin and peeling occurs, it is recommended that the povidone-iodine be washed off with water in a timely manner, and not to continue to allow it to stimulate the foreskin, otherwise the condition will become more and more serious. When the symptoms mentioned above appear, you should go to a regular hospital in time for medical consultation, so that the professional doctor can clarify the cause of the disease and treat it as soon as possible.