Irritable bowel syndrome is a functional disorder of the gastrointestinal tract in which no substantial changes in the gastrointestinal tract occur. In contrast, enteritis is an inflammation or destruction of the intestinal wall that can lead to intestinal ulcers and narrowing of the intestinal lumen. Irritable bowel syndrome and enteritis are easily confused. Both are chronic conditions that cause abdominal pain, cramping and diarrhea. However, despite similar symptoms, these two conditions are quite different. 1. Irritable bowel syndrome is a functional bowel disease characterized by abdominal discomfort or pain with changes in bowel habits. Clinical manifestations lack specificity and vary widely among individuals, mainly manifesting as chronic diarrhea or constipation, abdominal discomfort, etc. It is a functional disease, i.e., there is no specific organic change. The onset of irritable bowel syndrome is mostly related to psychosomatic factors, and the prognosis is better. 2. There are more types of enteritis, which can be categorized into infectious and non-infectious enteritis, such as pseudomembranous enteritis, ulcerative colitis, Crohn’s disease and so on. The performance of different enteritis is different, for example, Crohn’s disease lesions mainly invade the end of the ileum, abdominal pain is mostly located in the right lower abdomen or umbilicus.