Massive proteinuria refers to 24-hour urine protein quantitative greater than 3.5g, commonly found in nephrotic syndrome and so on, the treatment includes general treatment, symptomatic treatment, immunosuppressive treatment, complications prevention and treatment.
1. General treatment: pay attention to rest, avoid going to public places and prevent infection, low-salt, low-fat, high-quality and low-protein diet.
2. Symptomatic treatment: including diuresis, reduce swelling, reduce urine protein, therapeutic drugs including furosemide, spironolactone, ACEI/ARB drugs, and so on.
3. Immunosuppressive therapy: select the therapeutic drugs and determine the course of treatment according to the pathological results of renal biopsy, including glucocorticoids such as prednisone, immunosuppressive agents such as cyclophosphamide, cyclosporine, etc.
4. Complications prevention and treatment: actively preventing and treating infections, thrombosis and embolism complications, acute kidney injury, protein and fat metabolism disorders, etc. Patients with massive proteinuria should go to the hospital promptly.
Patients with large amounts of proteinuria should go to the hospital in a timely manner, under the guidance of professional physicians. Drugs should be used in accordance with medical advice, do not self-medication.