Spironolactone belongs to the aldosterone inhibitor class of drugs, the use of this drug in dermatology, mainly applied to patients with a large amount of sebum overflow produced by a series of skin diseases, such as seborrhea, seborrheic alopecia, acne vulgaris and so on. Because the drug has a certain inhibition of the active function of sebaceous glands, so the use of this drug may be to a certain extent to control the production of sebum on the head and face of the patient, so as to produce a therapeutic effect on some related diseases. For example, after suppressing the sebum overflow, it will also reduce the possibility of locally stimulating Malassezia infection to a certain extent, thus being able to treat seborrheic dermatitis.