Will the disease worsen if the wrong medication is used? Should I stop or reduce the medication immediately if it is not effective? Generally speaking, it will not worsen the disease, but will delay the treatment and cause chronicity. Therefore, the initial diagnosis and treatment should be tailored by an experienced doctor at a regular specialized hospital to help patients choose the more appropriate type of medication, dosage, course of treatment and review interval. When there is no efficacy, some of them are due to slow onset, short course of treatment and insufficient dose of medication, so you should not stop or reduce the medication privately. Are symptoms such as tremors in the limbs, dull eyes and slow movement after taking the medication side effects or aggravation of the disease? Is it necessary to stop or change the medication if side effects occur? Symptoms such as tremor of the limbs, dullness of gaze and slowed movement after taking medication are usually extrapyramidal side effects and excessive sedation of the medication, which can be combined with treatment with benzhexol hydrochloride (Antan) and, if necessary, antipsychotics can be reduced. What do I need to pay attention to when stopping and changing medication? How to make a safe transition? Discontinuation and change of medication should be done under the guidance of a doctor. Schizophrenia should be treated for a long time to avoid relapse; the need for medication change should be evaluated by a doctor to guide the method of medication change. A crossover approach is generally chosen for medication changes, with the original medication being gradually reduced and the newly added medication gradually increased, usually completed in 2-4 weeks. Does schizophrenia in children require lifelong medication? Schizophrenia is a chronic, highly relapsing, disabling disease that has a great impact on the social function of patients, their families, and with multiple relapses, irreversible damage to the patient’s brain can occur. Children with schizophrenia have an early onset, often have a prolonged course, a high relapse rate, and a poor prognosis, while medication only relieves psychiatric symptoms and restores social function, and does not cure it. No better alternative to psychotropic medication for schizophrenia has been found, and antipsychotics are the most important aspect of treatment for the disorder. Therefore, long-term or even lifelong medication should be adhered to. Is there a long term solution for children who do not want to take medication? Because treatment of schizophrenia is a long-term process, medication adherence becomes important. For patients who tend to miss or refuse to take medication, have a sense of shame about taking medication, and have trouble taking medication, consider using once-a-day oral medications such as paliperidone extended-release tablets and olanzapine, and a long-acting medication that is taken once a week is pentoxifylline. Long-acting injections are even more convenient drugs. The new antipsychotic injection paliperidone palmitate (Sunstar) is injected once a month, which is fast-acting, safe and effective, with few side effects, and the injection can be stored at room temperature; Risperidone microspheres (Hengde) is injected once every 2 weeks, which has a slow onset of action and high storage conditions, and the cost of the above two drugs is relatively high. The classical antipsychotic injection haloperidol decanoate (Halidol) is injected once every 3 to 4 weeks, and fluphenazine decanoate is injected intramuscularly once every 2 weeks; these two drugs are inexpensive, but have relatively large side effects.