The main symptoms of leukemia patients may include fever, liver and spleen enlargement, enlarged lymph nodes, pallor, malaise, petechiae and purpura, bone pain, and claudication. Normal blood cells are white blood cells, red blood cells and platelets. When these cells have excessive abnormal proliferation and differentiation, a large number of non-functional cells are produced, which not only don’t work but also infiltrate and destroy everywhere, restricting the proliferation of other cells and leading to the occurrence of leukemia. 1. Fever: recurrent fever accompanied by weight loss. 2. Enlargement of liver and spleen: this is caused by leukocyte infiltration, etc. It may be accompanied by anorexia and enlargement of abdomen. 3. Enlargement of lymph nodes: painless enlargement of cervical lymph nodes, inguinal lymph nodes, and lymph nodes of the medial epicondyle of the humerus may be present, which is hard on pressure, adherent to the surrounding tissues, and elastic. 4. Pallor, fatigue, petechiae and purpura: anemia and bleeding associated with erythrocyte and thrombocytopenia. 5. bone pain, claudication or refusal to bear weight: suggestive of bone infiltration. Acute myelogenous leukemia and chronic myelomonocytic leukemia are most common in adults, and acute lymphoblastic leukemia is more common in children. Currently, there are mainly chemotherapy, cellular immunotherapy, hematopoietic stem cell transplantation, targeted drugs and other treatment means. Leukemia is not an incurable disease. Even if you have leukemia, the disease can be controlled very well through active treatment. We should keep an optimistic mind to face the disease positively.