Omeprazole stomach bloating may be caused by drug factors, may be chronic gastritis, peptic ulcer and other disease factors, the former caused by the symptoms are not serious can continue to take medication, the latter caused by the need for treatment under the guidance of a doctor, such as dietary adjustments, domperidone and other medications. 1. drug factors: omeprazole can cause gastrointestinal distension adverse reactions, so there will be the symptom of eating omeprazole stomach distension, can tolerate abdominal distension of patients can continue to use the drug treatment, can not be tolerated can be replaced with other drugs. 2. Disease factors: the need to take omeprazole is usually suffering from digestive system diseases, such as chronic gastritis, peptic ulcer and so on. Such patients should maintain small meals, avoid overeating, maintain a light and easy to digest diet; can also use the gastrointestinal dynamics of drug therapy, such as domperidone, mosapride, etc., to alleviate the symptoms of abdominal distension. The symptoms of bloating in the stomach after taking omeprazole if the symptoms are not relieved or aggravated is recommended to go to the hospital, follow the doctor’s instructions for treatment.