The harmful effects of long-term consumption of Ganoderma spore powder mainly lie in affecting patients to develop allergies. For example, skin allergy appears red, swollen, hot, painful, even rash, drug rash, and also induced mucous membrane edema, such as laryngeal edema, which needs emergency treatment. Long-term application of Ganoderma spore powder is not good for children because it may contain hormone-like effects, which is not conducive to children’s application. In addition, Ganoderma spore powder can also affect the blood clotting function, which can easily cause patients to have bleeding gums and intestinal bleeding. Ganoderma spore powder has strong health functions, such as lowering blood sugar, protecting the heart and brain vessels, protecting the liver, and a series of benefits such as anti-aging and regulating neurasthenia.