The causes of sudden nausea and vomiting in sleep are physiologic and pathologic. Physiological causes include early pregnancy reaction, dietary causes, etc. Pathological causes include reflux esophagitis, duodenal ulcer, acute cerebrovascular disease, Meniere’s syndrome and so on. 1. Physiological causes: women of childbearing age who have sex need to consider the early pregnancy reaction, which is related to the hormonal changes in the body; eating greasy or stimulating diets before going to bed and lying down can lead to reflux, resulting in the above symptoms. 2. Pathological causes: such as reflux esophagitis can also have acid reflux, heartburn symptoms; such as duodenal ulcer can also have nighttime stomach pain, hunger stomach pain; such as acute cerebrovascular disease has a history of hypertension, preferred in the middle-aged and elderly; such as Meniere’s syndrome can also have tinnitus, hearing loss and other symptoms, preferred in young people. If you have sudden nausea and vomiting while sleeping, it is recommended that you consult a doctor in time to clarify the cause.