The condition of very sore nipples in early pregnancy needs to be treated according to the specific situation, which may include general treatment, physiotherapy and medication. The occurrence of this situation is considered to be related to hormonal changes and may also be caused by nipple trauma. 1. Early pregnancy, due to the increased secretion of estrogen and progesterone, can cause breast follicle and lobular hyperplasia, as well as breast enlargement. During the enlargement period, there may be slight swelling and pain, and the nipple also has the symptom of pain. However, these symptoms are temporary, do not last long and can be relieved on their own. Physical therapy such as massage and hot compresses can also be used under the guidance of a doctor to relieve nipple pain. 2. If you rub your nipples hard when bathing or wear rough underwear, long-term friction of the nipple by external forces can lead to nipple trauma and pain in the nipple and surrounding skin. If accompanied by infection, local topical iodophor can be used, or oral penicillin treatment under the guidance of a doctor, but do not take medication without authorization. During pregnancy, wear loose and soft underwear, take a shower gently, and do not rub your nipples hard.