If the stomach is uncomfortable after taking Rosuvastatin, you can follow the doctor’s instructions to choose to change the drug, symptomatic treatment and other methods. 1. Change drugs: patients can be examined by a physician, follow the doctor’s instructions to change the drug treatment, such as replacing Ashuvastatin for lipid-lowering treatment. However, liver and kidney function, as well as creatine kinase, blood glucose and other indicators should be monitored at all times while taking the drug. Serious liver and kidney function impairment, myopathy patients and pregnant and lactating women need to pay attention to the contraindications involved in the replacement of drugs. 2. Symptomatic treatment: If the patient can tolerate the gastrointestinal reaction, and there is no pathologic change after examination, you can treat the symptoms. Such as heartburn can choose omeprazole and other proton pump inhibitors for gastric treatment. However, adverse reactions such as nausea and constipation should be noted during use. Severe renal insufficiency and infants are prohibited. It is recommended that if patients have any discomfort, they must go to the regular hospital to improve the relevant examination and follow the doctor’s instructions for standardized treatment.