Hepatitis B is hepatitis B disease, hepatitis B disease cured generally only surface antigen turn negative, if it is acute hepatitis B, generally can be cured. If it is chronic hepatitis B, the chances are smaller. Hepatitis B disease is mainly due to the infection of hepatitis B virus caused by, can cure need to be based on the patient’s specific situation. If the patient is acute hepatitis B, after timely and regular treatment, the general prognosis is good, can be cured. If the patient has chronic hepatitis B, it is more difficult to be cured completely, but most of them are in the status of carriers, and no treatment is needed when there is no abnormal liver function or histological damage of the liver. If it develops into cirrhosis or liver cancer appears, the prognosis is worse and cannot be cured. Hepatitis B patients should go to the hospital in time, take specific examination and treatment measures under the guidance of doctors, and should not delay to avoid aggravating the condition.