Pseudotuberculous nodules are lesions caused by worm eggs in schistosomiasis. Acute worm egg nodules are an acute necrotizing, exudative lesion caused by mature worm eggs. After 10 days of acute worm egg nodules, the trichomes within the eggs die, the eggs and necrotic material are removed, absorbed, or calcified, and the macrophages in the lesion diffuse into epithelioid cells and foreign multinucleated giant cells, forming granulomas similar to those of tuberculous nodules, which are known as pseudotuberculous nodules, i.e., chronic worm egg nodules. Pseudotuberculous nodules are lesions caused by worm eggs in schistosomiasis. Eggs may be deposited in the rectum, sigmoid colon, ascending colon, appendix, terminal ileum, and liver, but also in mesenteric and retroperitoneal lymph nodes, lungs, and brain and other organs. Deposited in various places of the eggs caused by the pathological changes are basically similar, the latter has acute and chronic. Intestinal lesions caused by schistosomiasis are generally within the distribution of the inferior mesenteric vein, to the colon, especially the rectum, descending colon and sigmoid colon for significant, small intestine lesions are rare, only seen in severe patients. The acute phase manifests as erythema of the intestinal mucosa with acute cicatricial inflammation, scattered punctate hemorrhages and small superficial ulcers. Microscopically, granulomas of worm eggs in the mucosa and submucosa are seen (acute phase).