Severe cerebral hemorrhage has a rapid onset and changes rapidly, just like the wind that moves well and changes several times, and the condition is critical. During the “Ninth Five-Year Plan” period, we proposed that for hypertensive cerebral hemorrhage, comprehensive medical and surgical treatment should be carried out, combining Chinese and Western medicine to complement each other’s shortcomings, giving full play to the characteristics of Chinese medicine and the overall control advantages of compound prescriptions, grasping the fundamentals, and combining the basic treatment principles based on commonality and individuality. Zhang Peng, Department of Orthopedics, People’s Hospital of Qingfeng County, China The clinic should choose the appropriate surgical method to rapidly remove the hematoma, relieve the occupying pressure of the hematoma, lower the intracranial pressure and relieve the symptoms according to the patient’s specific condition, and then formulate the treatment rules and methods according to the patient’s condition and disease duration, select multiple drugs to carry out comprehensive treatment by multiple drug delivery routes with some emphasis on the application of basic treatment and symptomatic treatment. On the basis of this, we have undertaken the research on hematoma removal and Chinese medicine treatment of hypertensive middle and massive cerebral hemorrhage, which is a national scientific and technological research topic of the Ninth Five-Year Plan. The research program adopted comprehensive treatment measures targeting multiple factors, links, levels and targets, integrating the advantages of Chinese and Western medicine in the treatment of hypertensive middle and massive cerebral hemorrhage, bringing into play the emergency response capability of modern medicine for patients with acute and critical illnesses, using hematoma removal to rapidly relieve the occupying effect of the hematoma, lowering the intracranial pressure and relieving the symptoms, and gaining time for the effectiveness of other comprehensive treatment measures. Through evidence-based treatment, we carry out fractional treatment, which is pertinent to the condition and overall regulation, adjusting the balance of yin and yang qi and blood of human internal organs, improving clinical efficacy, reducing morbidity and mortality rate, and improving quality of life. Clinically, we randomly divided 201 patients into 103 cases in the treatment group and 98 cases in the control group. The treatment group applied a comprehensive salvage treatment plan (including surgical treatment, Chinese medicine identification treatment, and basic treatment), and the control group applied surgical treatment, Western medicine treatment, and basic treatment. The results at 28 days after treatment and at 6-month follow-up showed that the comprehensive TCM treatment improved the total clinical efficiency, reduced the morbidity and mortality rate, decreased the complications, and improved the quality of life of patients. The morbidity and mortality rates in the control group were similar to those reported in the literature for the surgical group, and the morbidity and mortality rates in the treatment group using the comprehensive salvage regimen were significantly lower than those in the literature for the medical group and the surgical group. Relevant literature studies suggest that the closed evidence of hypertensive middle and massive cerebral hemorrhage is dominated by Yang closed evidence, and the clinical efficacy and the degree of improvement of symptoms of Yang closed evidence tentatively suggest that clearing heat, pacifying the liver, breaking down blood stasis, cleaning phlegm, clearing the internal organs, and awakening the mind can represent the basic treatment of Yang closed evidence of hemorrhagic stroke, and reducing complications and complication mortality is one of the possible mechanisms of action of Chinese medicine for the effective treatment of hypertensive middle and massive cerebral hemorrhage after hematoma removal. The results of relevant animal experiments and literature studies suggest that the comprehensive rescue protocol has good clinical efficacy in patients with Yang-closure evidence of hypertensive middle and massive cerebral hemorrhage (hemorrhage ≥ 30 ml), is practical and feasible, and is worthy of further expansion of the sample and validation by multicenter cooperation to promote its application.