Most of the nodules in the chest will not disappear on their own, only the cystic nodules formed by cystic hyperplasia of the breast may change with the menstrual cycle to become smaller and softer. The only effective treatment is surgical excision. 2. Cystic hyperplasia of the breast, which can appear before the menstrual cycle with painful swelling of the breast and a palpable breast lump, and after the end of the menstrual cycle the symptoms can be relieved significantly. 3. Breast cancer, which is a painless nodule with unclear boundary and poor mobility, requires ultrasound examination and will not disappear.