Treatments for chloasma patients include searching for the cause of disease, topical drug treatment, systemic drug treatment, laser treatment and so on. 1. Finding the cause of disease: first of all, the cause of disease should be found and treated accordingly. For example, improving endocrine disorder, changing cosmetic type, avoiding sunlight exposure, etc. 2. Topical medication: decolorizing agents such as 2%~5% hydroquinone cream, 4% tretinoin, 15%~20% azelaic acid cream and compound arbutin cream can inhibit tyrosinase activity and reduce the production of pigment.0.025%~0.1% retinoic acid can affect the metabolism of melanin and has certain curative effect. Superoxide dismutase can reduce melanin production by inhibiting and scavenging oxygen free radicals. Chemical stripping with fruit acid and addition of decolorizing agent can achieve good results. 3. Systemic medication: oral vitamin C, vitamin E and tranexamic acid. 4. Laser treatment: Q-switched large spot low-energy laser and intense pulsed light have certain therapeutic effect on melasma. Melasma patients should go to the hospital in time and standardize the medication under the doctor’s guidance, do not blindly deal with it on your own.