Low platelets and low white blood cells, belong to two lineage reduction, it is recommended to consult a doctor, improve the examination, clarify the cause of the disease, according to the cause of the drug treatment and other methods. In routine blood test, when the platelet count is lower than 100×10^9/L and at the same time the white blood cell count is lower than 4.0×10^9/L, then it is a two-lineage reduction. It can be seen in aplastic anemia, systemic lupus erythematosus, influenza, rubella and other causes. 1. Aplastic anemia, perfect bone marrow aspiration and biopsy can find granulocytes, erythrocytes and megakaryocytes significantly reduced, resulting in a decrease in white blood cells, red blood cells and platelets. Treatment includes immunosuppressive therapy (cyclosporine) and hematopoietic promotion therapy (androgens). 2. Systemic lupus erythematosus (SLE) is an immune system disease, the autoantibodies produced can lead to the reduction of white blood cells and platelets, and it can be diagnosed by perfect immunological examination, and can be treated with immunosuppressant (cyclosporine). 3. Influenza and rubella are viral infections, which can also lead to a decrease in platelet and white blood cell counts. Diagnosis can be made on the basis of clinical symptoms, virological examination, and hematologic examination, and symptomatic treatment with antiviral (ganciclovir) is required after diagnosis. Low platelets and low white blood cells, it is recommended to consult a doctor in a timely manner, under the guidance of a professional doctor, standardized examination and treatment, drugs should be used as prescribed by the doctor.