The main causes of eye and mouth twitching are the following: 1. Meige syndrome, patients with Meige syndrome will have eye or mouth twitching, mostly bilateral, some patients keep pouting and blinking, after giving haloperidol and clonazepam orally the patient’s symptoms can be relieved. 2. Ask the patient if there is any previous history of facial neuritis, some patients with facial neuritis are prone to facial muscle spasms during the recovery period. If the twitching of the eyes or mouth is due to anxiety, nervousness or mental stimulation, the patient may be given Dexedrine or the anti-anxiety drug Lysop orally to relieve the symptoms.