For patients with chronic viral hepatitis B, if the right upper abdomen and the back of the swelling pain or hidden pain discomfort. First of all, the patient should observe the ultrasound of the upper abdomen, firstly, to see whether there are hypoechoic masses in the liver area, and secondly, to see whether there are gallbladder stones, cholecystitis, and intrahepatic choledocholithiasis or choledocholithiasis in the patient. If a patient has gallbladder stones, cholecystitis or intrahepatic bile duct stones, or common bile duct stones, further treatment should be considered. For patients with gallbladder stones combined with cholecystitis, laparoscopic cholecystectomy should be considered as early as possible if the stones are more than 1.5 cm or if the patient has recurrent cholecystitis. In addition, for some patients, if ultrasound found hypoechoic masses in the liver area, then the patient should also draw blood to check the alpha-fetoprotein to see if there is an elevation of alpha-fetoprotein. If alpha-fetoprotein is elevated, we should further check the patient’s upper abdomen enhanced CT and PET-CT examination if necessary, to comprehensively determine whether the patient has the possibility of primary tumor disease in the liver.