Clogged hair follicles with no hair growth are usually perifollicular keratosis, which can be treated with topical medications and oral medications, such as retinoic acid cream, vitamin A, and so on. Perifollicular keratosis may be related to metabolic disorders, heredity, vitamin deficiency and other factors, manifested as the appearance of normal skin color or reddish papules on the surface of the skin, the top of the lesion has a light brown keratin plugs, and inside there are curly hairs. 1. Topical medications: Topical medications include retinoic acid cream, tazarotene gel, urea cream, salicylic acid ointment, cod liver oil ointment, etc., which can soften or dissolve the keratin, and at the same time, topical moisturizing preparations, such as petroleum jelly, can alleviate the symptoms of dry skin. 2. Oral medication: Commonly used oral medications include vitamin A, vitamin E, or small doses of retinoic acid to improve symptoms. All of the above drugs should be used under the guidance of a professional doctor, avoid self-medication. Hair follicle clogging hair can not grow out, daily use of non-irritating, mild shower products, shower can be recommended by the doctor to use moisturizing cream, to a certain extent, can improve the appearance of the skin.