Does penicillin infusion for psoriasis help? It is not possible to generalize. In the case of punctate psoriasis, the onset of the disease is preceded by an infection of the upper respiratory tract, such as a streptococcal infection that can induce psoriasis. Patients may have fever, sore throat, and elevated white blood cells in the blood picture, when giving intravenous penicillin is helpful for the treatment of the disease. The rash of psoriasis will improve after the inflammation subsides, but in most cases, especially in common psoriasis, including plaque psoriasis or erythrodermic psoriasis, which has little to do with infection, penicillin infusion is not useful in this case. You have to choose for example Aviatica or Chinese herbal medicine to clear heat and detoxify the blood and dispel wind, together with topical medicine to treat.