“Wind and fire toothache” belongs to a common name, the common cause of this pain is endodontitis, periapical inflammation, etc., may involve drugs such as metronidazole, amoxicillin, cefuroxime. Commonly known as “wind and fire toothache”, mainly in the teeth in the inflammation, encounter cool things or hot things stimulate the pain will be very obvious, such as sucking cool wind or wind blowing may cause the symptoms of tooth pain aggravation, and even facial swelling, fever and other symptoms, these are commonly caused by pulpitis, periapical inflammation and other diseases. If tooth pain caused by pulpitis or apical periodontitis is diagnosed, root canal treatment is needed, and antibiotics such as metronidazole, amoxicillin, and cefuroxime can be used as prescribed by the doctor to control the infection. It is recommended that patients consult a doctor in a timely manner to clarify the cause of the disease, give targeted treatment, do not blindly self-medication.