Usually, the hepatitis B DNA virus is less than 100IU/ml, we can be clinically referred to as turn negative. The normal value of hepatitis B DNA is less than 100IU/ml, if the value is more than 100IU/ml, it means that there may be hepatitis B virus carries, the value is less than 100IU/ml, we can be clinically known as negative, this situation is common in the hepatitis B patients taking antiviral drugs, the virus will be gradually reduced, and slowly tends to be within the range of normal value. If the hepatitis B DNA virus is less than 100IU/ml, it is recommended to do further tests such as hepatitis B 5, liver function, liver ultrasound, alpha-fetoprotein, etc., and determine whether treatment is needed or revise the treatment plan through the results of these tests.