The causes of knee pain while sleeping are complex and are as follows: 1. Generally, knee pain while sleeping is mostly considered to be related to degenerative strain on the knee joint. In general, the sensation may not be obvious during the day, and the sensation of nerve conduction is more sensitive when sleeping, and it will be relatively obvious at night after the injury; 2, when the knee joint is in a long-term position, if there is a problem inside the joint, pain may exist when there is a sudden change in posture; 3, after the joint problem, or the patient’s physique has cold and damp factors, the Yang energy is relatively insufficient at night, and local stimulation will occur Nighttime pain; 4. Elderly patients may have local pain at night due to physical factors, such as osteoporosis factors.