There are many types of statins, including simvastatin, fluvastatin, pitavastatin, lovastatin, pravastatin, atorvastatin, and rasulvastatin. However, the common pharmacological effect is to inhibit cholesterol synthesis, lower cholesterol levels, and prevent and slow down the process of atherosclerosis. The specific which is better, need to choose according to the patient’s own situation. 1, for cardiovascular disease or have done heart stent, Rosuvastatin and Atorvastatin cholesterol-lowering effect is better; 2, for liver disease, biliary tract disease, such as pravastatin or Rosuvastatin is better, less damage to the liver; 3, people with serious kidney disease use Atorvastatin, the impact on kidney function is less; 4, if Those with diabetes or high blood sugar can choose pitavastatin and pravastatin, which have less effect on blood sugar; 5. Those with sleep disorders and cerebrovascular diseases can use resulvastatin or pravastatin, both of which are water-soluble drugs that do not pass the brain barrier and have less effect on the nervous system. Some studies have shown that statins, in addition to lowering LDL cholesterol levels, can stabilize and reverse plaques that have formed and are the cornerstone of coronary heart disease treatment. However, the side effects of statins should not be ignored as well. In particular, there are effects on liver and kidney function, rhabdomyolysis, weakness and the risk of new onset diabetes. Therefore, it is important to regularly review liver and kidney function, myoenzymes and blood glucose levels when taking such drugs orally, and to treat the problem symptomatically as soon as it arises.