For third-degree exposure wounds, rabies immunoglobulin is recommended. For primary and secondary exposure wounds, the rabies vaccine alone can produce protective antibodies, but for tertiary exposure, it is recommended that immunoglobulin be injected into the area around the animal bite. The body does not produce antibodies to neutralize the virus immediately after the rabies vaccine is injected, usually as early as about 14 days after the injection. Rabies immunoglobulin is a passive immune agent that produces specific protective antibodies for the body, thus producing a protective effect before the injection of rabies vaccine produces antibodies. Especially if the patient suffers from immunodeficiency diseases, long-term use of immunosuppressive drugs, head and face exposure injuries, also need timely injection of rabies immunoglobulin, it is recommended to consult the emergency department of the regular hospital for injection, do not blindly treat yourself, so as to avoid delaying the condition.