There is no clear data to support the exact duration of how long to take Yusuf (ursodeoxycholic acid capsule) to lower bilirubin. Ursodeoxycholic acid capsule is used for cholestatic liver disease, bile reflux gastritis and other diseases. Ursodeoxycholic acid capsule can promote the metabolism and excretion of bilirubin. The duration of the medication is not clearly defined at present, and needs to be determined by the doctor according to the patient’s specific condition. Adverse reactions such as loose stools or diarrhea may occur after use of the drug, which can be gradually relieved after stopping the drug. Elderly, pregnant and lactating women should use the drug with caution. This medication should not be combined with other medicines such as Colestipol at the same time. This drug is contraindicated in people who are allergic to this drug or the ingredients in the formula, acute cholecystitis, impaired gallbladder function, and so on. The specific dosage and usage of the above medicines should follow the doctor’s instructions and should not be used on its own to avoid adverse reactions.