Pus is mainly referred to as a boil in medical terms and whether you need to squeeze out a boil on your hand depends on the stage of the attack of the boil. In the initial or acute stage of the attack, do not squeeze it out, while in the mature stage you can go to the hospital and have it cut open by a doctor to squeeze out the pus. If the boil is in the early stage or acute attack stage, do not squeeze out the pus. This is due to the fact that during the early stage or acute attack of the disease, the local capillaries are in a state of dilatation, and the blood flow rate is relatively fast, and the process of squeezing will easily lead to the diffusion of inflammatory factors into the soft tissues around the pus bag, thus further aggravating the local inflammatory reaction. Generally, the initial stage of boils can be drained of pus with medication under the guidance of a doctor. Antibiotics such as cefaclor can be used, together with topical fusidic acid ointment and ichthyolite ointment. If the boil is in the mature stage, meaning that the inflammation has changed from a large red and swollen state to a limited and fluctuating sensation, or the effect of medication is unsatisfactory, you can go to the hospital and have the doctor perform a minor surgical operation to cut open and squeeze out the pus, which can speed up the recovery of the boil. It is recommended to go to the dermatology department of the hospital in time, under the guidance of professional doctors to treat the symptoms, do not squeeze, do not self-medication.